Camptothecine CAS:7689-03-4

Camptothecine 

Basic info:

CAS:7689-03-4

Melting point: 260 ° C (dec.) (lit.)

Specific rotation: D25+31.3 ° (in chloroform solvent, 8:2)

Boiling point: 482.73 ° C (rough estimate)

Density: 1.3112 (rough estimate)

Refractive index: 1.5700 (estimate)

Storage conditions: 2-8 ° C

Solubility: chloroform/ethanol (4:1): 4 mg/mL

Acidity coefficient: pKa 10.83 (Uncertain)

Form: solid

Color: yellow

Water solubility: insoluble

Merck141735

BRN: 631069

Stability: Stable for 1 year from date of purchase as supplied Solutions in DMSO may be stored at -20 ° C for up to 3 months

Product description:

Camptothecin (CPT) is a cytotoxic quinoline alkaloid that inhibits DNA topoisomerase I (topoI). It was created by M. in 1966 E. Wall and M C. Wani discovered it in the systematic screening of natural products of anti-cancer drugs. It is isolated from the bark and stem of the camphor tree. Xishu is a tree native to China and used in traditional Chinese medicine to treat cancer. CPT has shown significant anti-cancer activity in preliminary clinical trials, but with low solubility and high drug adverse reactions. Due to these drawbacks, synthetic and pharmaceutical chemists have developed a large number of synthetic methods for camptothecin and its derivatives to increase the benefits of the chemical substance and achieve good results.

Company Introduction：

Our company's main products include plant essential oils, synthetic flavors and natural flavors. The company's products can be used in food and beverage, daily chemical and other industries; Our company always attaches great importance to product quality and brand reputation, and strictly implements product quality and environmental management control. It has passed various certifications such as China GPM, ISO9001, ISO14001, KOSHER,HALAL and Continental Analysis; Our company's product users throughout the world more than 30 countries and regions, after more than 10 years of technology accumulation and market development, the company has accumulated high-quality, stable customer channels and resources, and established a good cooperative relationship with the international and domestic famous enterprises, high-quality products and services.

Our company always values product quality and brand reputation, strictly implements product quality and environmental management control, and has passed various certifications such as GPM, ISO9001, ISO14001:, Kosher, HALAL Continental Analysis, etc.

Our company's product users cover more than 30 foreign companies and regions. After more than ten years of technological accumulation and market development, the company has accumulated a group of high-quality customer groups, stable customer channels and resources, and established good cooperative relationships with more than 100 domestic and foreign enterprises.

Packing & shipping 

1. Double polyethylene bags inside, and high-quality standard carton drum outside,1kg for the Foil bag, 25kg for drum or we also can customize the package according to customers demands.

2. Shipping by express, air, Sea, and some special line to most Countries

3. Normally for the small quantity, we will ship them by DHL, Fedex, UPS, special line and so on, for big quantity By air, Sea, and some special line to most Countries.

Our service:

1.Free sample.

2.Owning cultivation base as 100% Natural material stable source.

3.Manufacturer direct supply, Powerful R&D team and advanced test center.

4.Leading plant extract manufacturer in China.

5.No excuse return of goods.

FAQ:

1. How do you ensure your product and service quality?

A:All of our processes strictly adhere to 1S0 9001 procedures and we are equipped with state of the art quality control facilities.

2. How about lead time?

A:Usually, within 10 days, according to the order quantity.

3.How about the payment?

A:We support most mainstream payment methods.T/T, L/C, D/P, D/A, O/A,Cash, Western Union, Money Gram, etc.

4. Can you send free samples?

A:Yes, we can send free samples for most products. Please feel free to send inquiry for specific requests.

5. Do you offer technical supports for the products?

A:Yes, we have a professional technical support team and can provide unique technical .